People of an older age, taking other medicines that affect the stomach, or who drink more than 3 glasses of alcohol per day may be more at risk. Other side effects including tinnitus (ringing in the ears) have also been reported.
Most NSAIDs have been associated with an increased risk of serious cardiovascular events including stroke or heart attack. May increase bleeding time especially if given with other medicines that also delay blood clotting.
May interact with some other medicines such as warfarin, SSRIs, ACE inhibitors, and diuretics. Note: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects.
Taking Voltaren with food may help with stomach-related side effects. Blood counts and liver enzymes may need monitoring periodically.
Time to peak effect varies from 30 minutes to 3-5 hours depending on the formulation of Voltaren taken. ACE inhibitors or Arms, such as captopril, enalapril, or losartan antibiotics, such as ciprofloxacin or vancomycin anticoagulants (blood thinners) such as apixaban, dabigatran, fondaparinux, heparin, or warfarin antidepressants, such as citalopram, Escitalopram, fluoxetine, or fluoxetine antifungals, such as voriconazole beta blockers, such as acebutolol, atenolol, bisoprolol, or carvedilol bisphosphonates, such as alendronate diuretics (water pills), such as chlorthalidone, chlorothiazide, or hydrochlorothiazide HIV medications (e.g., Sterile, tenofovir) other non-steroidal anti-inflammatories (NSAIDs), such as celecoxib, eidola, ibuprofen, Motorola, meloxicam, nabumetone, or naproxen sulfonylureas (a type of diabetes medication), such as glimepiride, glyceride, or glipizide supplements, such as glucosamine, omega-3 fatty acids, vitamin E others, such as cyclosporine, lithium, methotrexate, penetrated, pirfenidone, or tacrolimus.
Drinking alcohol while taking Voltaren may increase the risk of gastrointestinal-related side effects or kidney damage. Note that this list is not all-inclusive and includes only common medications that may interact with Voltaren.
You should refer to the prescribing information for Voltaren for a complete list of interactions. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Round, pink, imprinted with Voltaren XR, 100 This effect can occur without warning symptoms at any time while taking this drug.
Stop taking diclofenac and get medical help right away if you notice any of the following rare but serious side effects: bloody or black/tarry stools, persistent stomach / abdominal pain, vomit that looks like coffee grounds, chest/jaw/left arm pain, shortness of breath, unusual sweating, weakness on one side of the body, sudden vision changes, slurred speech. Read the Medication Guide provided by your pharmacist before you start using diclofenac and each time you get a refill.
Take this medication by mouth with a full glass of water (8 ounces / 240 milliliters) unless your doctor directs you otherwise. If you experience stomach upset with this medication, you may take it with food, milk, or an antacid.
However, this may slow absorption and delay pain relief, especially if you are not taking this medication on a regular schedule. Doing so can destroy the special coating on the tablet and may increase side effects.
For chronic conditions such as arthritis, continue taking it as directed by your doctor. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects.
Check your blood pressure regularly and tell your doctor if the results are high. Get medical help right away if any of these rare but very serious side effects occur: signs of kidney problems (such as change in the amount of urine), unexplained stiff neck.
Kidney problems can sometimes occur with the use of NSAID medications, including diclofenac. Problems are more likely to occur if you are dehydrated, have heart failure or kidney disease, are an older adult, or if you take certain medications (see also Drug Interactions section).
Daily use of alcohol and tobacco, especially when combined with this medicine, may increase your risk for stomach bleeding. Older adults may be at greater risk for stomach/intestinal bleeding, kidney problems, heart attack, and stroke while using this drug.
Before using this medication, women of childbearing age should talk with their doctor(s) about the benefits and risks (such as miscarriage, trouble getting pregnant). It is not recommended for use during the first and last trimesters of pregnancy due to possible harm to the unborn baby and interference with normal labor/delivery.
Do not start, stop, or change the dosage of any medicines without your doctor's approval. Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (aspirin, NSAIDs such as celecoxib, ibuprofen, or Motorola).
These drugs are similar to diclofenac and may increase your risk of side effects if taken together. However, if your doctor has directed you to take low-dose aspirin to prevent heart attack or stroke (usually at dosages of 81-325 milligrams a day), you should continue taking the aspirin unless your doctor instructs you otherwise.
Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe stomach pain, vomit that looks like coffee grounds, extreme drowsiness, slow/shallow breathing, seizures.
Laboratory and/or medical tests (such as blood pressure, complete blood count, liver and kidney function tests) may be performed periodically to monitor your progress or check for side effects. Non-drug treatment that is approved by your doctor for arthritis (such as weight loss if needed, strengthening and conditioning exercises) may help improve your flexibility, range of motion, and joint function.
If you are prescribed this drug on a regular schedule (not just “as needed”) and you miss a dose, take it as soon as you remember. Consult your pharmacist or local waste disposal company. Information last revised April 2020.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Generic Name: diclofenac (dye KLEE fen AK) Brand Name: Voltaren Diclofenac works by reducing substances in the body that cause pain and inflammation.
Voltaren gel is used to treat osteoarthritis of the knees and hands. You should not use Voltaren if you have a history of allergic reaction to aspirin or NSAIDs (non-steroidal anti-inflammatory drugs).
Voltaren increase your risk of fatal heart attack or stroke. These conditions can occur without warning while you are using this medicine, especially in older adults.
Diclofenac can affect ovulation, and it may be harder to get pregnant while you are using this medicine. Follow the directions on your prescription label and read all medication guides.
Ask your pharmacist if you have any questions about the brand of diclofenac you receive at the pharmacy. Do not take extra medicine to make up the missed dose.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Avoid taking aspirin or other NSAIDs unless your doctor tells you to.
Ask a doctor or pharmacist before using other medicines for pain, fever, swelling, or cold/flu symptoms. They may contain ingredients similar to diclofenac (such as aspirin, ibuprofen, ketoprofen, or naproxen).
Get emergency medical help if you have signs of an allergic reaction to Voltaren (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, feeling short of breath.
Heart or blood pressure medication, including a diuretic or “water pill”; Other drugs may interact with diclofenac, including prescription and over-the-counter medicines, vitamins, and herbal products.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.