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Are Zpacks Effective For Covid

author
Christina Perez
• Friday, 18 December, 2020
• 12 min read

PAK, also known as azithromycin or Zithromax, could be a critical tool in preventing and treating COVID-19 -19 coronavirus, according to Professor Michael P. Anti, MD-PhD and Chair of Translational Medicine at Salford University in the UK. I recently spoke with Professor Anti to unpack his hypothesis and call for immediate clinical trials of PAK and other extremely inexpensive, generic antibiotics for COVID-19 -19 patients.

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Anti's lab goes on, “Clinically, it appears what is leading to fatalities in older patients is the very strong inflammatory reaction and the resulting fibrosis. PAK has made headlines after doctors around the world such as the widely publicized French clinic trials and New York and New Jersey physicians have found promising results on the front-lines of coronavirus using it in combination with another generic drug hydroxychloroquine.

“Azithromycin is known to stop the production of cytokines, a torrent of inflammatory mediators that trigger life-threatening lung inflammation in coronavirus patients. Other FDA-approved generic antibiotics such as doxycycline (which costs around 10 cents per dose) that target senescent cells could also be fruitful to study in clinical trials.

We need medical groups, philanthropists, and entrepreneurs to support and develop clinical trials using PAK and doxycycline to investigate treatment and prevention of COVID-19 -19. If PAK or doxycycline alone or in combination can be clinically shown to fight coronavirus, it may be an easier protocol to scale since these antibiotics are extremely inexpensive and are some of the most widely prescribed drugs in the world today.

For our historic fight with COVID-19 -19, we must take action in pursuing clinical trials for these potentially revolutionary antibiotic therapies right under our noses. PAK, also known as azithromycin or Zithromax, could be a critical tool in preventing and treating COVID-19 -19 coronavirus, according to Professor Michael P. Anti, MD-PhD and Chair of Translational Medicine at Salford University in the UK.

I recently spoke with Professor Anti to unpack his hypothesis and call for immediate clinical trials of PAK and other extremely inexpensive, generic antibiotics for COVID-19 -19 patients. This regulatory hurdle precludes natural substances that cannot be patented from being properly researched and tested for illnesses because companies cannot afford the cost to prove the efficacy of something that any organization would be able to sell afterwards.

Anti's lab goes on, “Clinically, it appears what is leading to fatalities in older patients is the very strong inflammatory reaction and the resulting fibrosis. PAK has made headlines after doctors around the world such as the widely publicized French clinic trials and New York and New Jersey physicians have found promising results on the front-lines of coronavirus using it in combination with another generic drug hydroxychloroquine.

“Azithromycin is known to stop the production of cytokines, a torrent of inflammatory mediators that trigger life-threatening lung inflammation in coronavirus patients. Other FDA-approved generic antibiotics such as doxycycline (which costs around 10 cents per dose) that target senescent cells could also be fruitful to study in clinical trials.

We need medical groups, philanthropists, and entrepreneurs to support and develop clinical trials using PAK and doxycycline to investigate treatment and prevention of COVID-19 -19. If PAK or doxycycline alone or in combination can be clinically shown to fight coronavirus, it may be an easier protocol to scale since these antibiotics are extremely inexpensive and are some of the most widely prescribed drugs in the world today.

A lot of attention has shifted to the malaria drug hydroxychloroquine for treatment of COVID-19 -19, the disease caused by the novel coronavirus. However, because the drugs are approved for malaria, lupus and rheumatoid arthritis, physicians have broad latitude for using them “off-label” for COVID-19 -19.

Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, is taking a more cautious, scientific approach. A Wuhan Institute of Virology study indicated it can be fatal in adults at twice the daily recommended amount, which is only one gram.

According to China’s Ministry of Sciences and Technology, which ran trials of chloroquine in about 130 patients, the drug decreased the severity of COVID-19 -19 and increased the speed of viral clearance. Side effects include upset stomach, diarrhea, nausea, vomiting or abdominal pain.

While production of these drugs increases, physicians will likely use the combination and others to treat COVID-19 -19 under hospital conditions, if they can acquire enough doses of them. Individuals hoarding them will make that more difficult and people using them without physician supervision run serious risks of side effects and potential overdoses.

He did not know he was infected at the time, but he did tell her he had attended a birthday party in the South Bay where several guests later tested positive. When her coughing got worse and the fever wouldn’t go away, Dr. Solomon was admitted to Torrance Memorial Hospital.

Solomon says hydroxychloroquine can cause side effects like liver toxicity. Solomon says she’s concerned about the long-term effects of COVID-19 -19 in our systems and hopes there will be more research conducted to identify and track any potential chronic problems.

Though azithromycin is an antibiotic and thus ineffective alone against viruses, some clinicians have seen limited success in COVID-19 -19 coronavirus disease patients when adding it to chloroquine (Aralen) and/or hydroxychloroquine (Plaquenil) in the sickest patients. As of March 30, 2021, there is little solid evidence for this drug combination's effectiveness in general against COVID-19 -19, however.

The initial COVID-19 -19 data about azithromycin came from just a few patients in an observational “open label” study, which makes it difficult to isolate variables and say whether a particular drug is working. Chloroquine and hydroxychloroquine are decades-old malaria drugs French doctors tested on coronavirus patients.

Six patients in the tiny study of about 20 happened to also be on azithromycin for other conditions while also being administered the malaria drugs. Researchers are still testing the malaria drugs and their combination with azithromycin to fight coronavirus.

The FDA has released both malaria drugs for emergency use in COVID-19 -19, despite the dearth of evidence. For most infections, azithromycin is taken once daily for a relatively short course of treatment (usually five days).

Azithromycin, like all Caroline antibiotics, prevents bacteria from growing by interfering with their ability to make proteins. It is an unusual antibiotic in that it stays in the body for quite a while (has a long half-life), allowing for once-a-day dosing and for shorter treatment courses for most infections.

Azithromycin (Zithromax, PAK, Trial, Max) is an antibiotic prescribed for the treatment of a wide variety of bacterial infections such as Otis media (middle ear infection), laryngitis, bronchitis, pneumonia, and others. See the latest news updates and information on the Coronavirus COVID-19 -19 outbreak.

Take this quiz to learn the three conditions that make up the pulmonary disease called... Take the Ear Infection (Otis Media) Quiz to learn the risks, causes, symptoms and...

Take the Pneumonia Quiz on Medicine to learn more about this highly contagious, infectious disease. Take the Strep (Streptococcal) Throat Infection Quiz to learn about causes, symptoms, treatments, prevention methods, diagnosis, ...

Signs and symptoms are headache, fever, and facial tenderness, pressure, or pain. Treatments of sinus infections are generally with antibiotics and at times, home remedies.

There are many causes of an excessive or severe cough including irritants like cigarette and secondhand smoke, pollution, air fresheners, medications like beta blockers and ACE inhibitors, the common cold, HERD, lung cancer, and heart disease. Natural and home remedies to help cure and soothe a cough include stay hydrated, gargle saltwater, use cough drops or lozenges, use herbs and supplements like ginger, mint, licorice, and slippery elm, and don't smoke. Prescription drugs that help cure a cough include narcotic medications, antibiotics, inhaled steroids, and anti-reflux drugs like proton pump inhibitors or PPI's, for example, omeprazole (Prilosec), omeprazole (Cipher), and pantoprazole (Proton ix).

If symptoms occur, they may include persistent bad breath, sore throat, difficulty swallowing, ear pain, and cough. Symptoms and signs include cough, fever, shortness of breath, and chills.

Tonsillitis is a contagious infection with symptoms of bad breath, snoring, congestion, headache, hoarseness, laryngitis, and coughing up blood. Treatment of tonsillitis and adenoids include antibiotics, over-the-counter medications, and home remedies to relieve pain and inflammation, for example, salt water gargle, slippery elm throat lozenges, sipping warm beverages and eating frozen foods (ice cream, popsicles), serrapeptase, pa pain, and andrographism Some people with chronic tonsillitis may need surgery (tonsillectomy or adenoidectomy).

STDs are diagnosed with tests that identify proteins or genetic material of the organisms causing the infection. Impetigo is a contagious skin infection caused by staph and strep bacteria.

Symptoms of nebulous impetigo include small blisters on the nose, face, arms, or legs and possibly swollen glands. Treatment involves gentle cleansing, removing the crusts of popped blisters, and the application of prescription-strength mupirocin antibiotic ointment.

Examples of STDs include, android, chlamydia, gonorrhea, granuloma inguinal, lymphogranuloma venereal, syphilis, genital herpes, genital warts, trichomoniasis, pubic lice (crabs), and scabies. Chronic cough is a cough that does not go away and is generally a symptom of another disorder such as asthma, allergic rhinitis, sinus infection, cigarette smoking, HERD, postnasal drip, bronchitis, pneumonia, medications, and less frequently tumors or other lung disease.

Chronic cough treatment is based on the cause, but may be soothed natural and home remedies. The most common cause of acute laryngitis is infection, which inflames the vocal cords.

Cystic acne is distinguished by painful nodules on the chest, face, neck, and back. Treatment may incorporate the use of hormonal therapies, oral antibiotics, and prescription medications.

Though sore throats are typical with colds, they are uncommon with COVID-19 -19 infections and the flu. The signs and symptoms of pelvic inflammatory disease include: fever, vaginal discharge with a foul odor, abdominal pain, including pain during intercourse, and irregular vaginal bleeding.

Pelvic inflammatory disease treatment includes several types of antibiotics. Transmission of COVID-19 -19 occurs mainly through contact with respiratory sections from an infected person, however, fecal contamination may also spread the virus.

Symptoms start off flu-like and progress to coughing, fever, shortness of breath, shaking chills, headache, loss of sense of taste and/or smell, muscle pain, and sore throat. Causes of acute bronchitis include viruses and bacteria, which means it can be contagious.

Acute bronchitis caused by environmental factors such as pollution or cigarette smoke is not contagious. Common symptoms for acute bronchitis include nasal congestion, cough, headache, sore throat, muscle aches, and fatigue.

Acute bronchitis in children also my include runny nose, fever, and chest pain. Treatment for acute bronchitis are OTC pain relievers, cough suppressants (although not recommended in children), and rest.

The outcome of the disease leaves the body malnourished, with bulky and fouls smelling stools, vitamin insufficiency, gas, painful or swollen abdomen, infertility, susceptible to heat emergencies, and respiratory failure. Symptoms mimic those of OCD, ADHD, and include motor and verbal tics.

Symptoms of COPD include shortness of breath, wheezing, and chronic cough. Treatment of COPD includes GOLD guidelines, smoking cessation, medications, and surgery.

Group A streptococcal infections are caused by group A streptococcus, a bacterium that causes a variety of health problems, including strep throat, impetigo, cellulitis, erysipelas, and scarlet fever. Chlamydia signs and symptoms may include painful urination, rectal irritation (parotitis), eye infections, and infertility.

Chronic bronchitis is a cough that occurs daily with production of sputum that lasts for at least three months, two years in a row. Causes of chronic bronchitis include cigarette smoking, inhaled irritants, and underlying disease processes (such as asthma, or congestive heart failure).

Rheumatic fever is a disease that sometimes occurs after a group A streptococcal infection of the throat. Symptoms and signs include CARITIG, polyarthritis, Scoff bodies, rash, Dagenham's chorea, and fever.

Treatment for rheumatic fever involves eliminating the bacteria with penicillin, erythromycin, or azithromycin. Further treatment focuses on alleviating the symptoms brought on by the body's immunologic response to the bacteria.

Symptoms and signs include fever, headache, nausea, vomiting, diarrhea, and rash. Causes of laryngitis are viral, bacterial, fungal, strenuous singing or talking, chemical irritants, and other underlying medical conditions.

Whooping cough commonly affects infants and young children but can be prevented with immunization with the vaccine. Trachoma is an infectious disease caused by the Chlamydia trachomas bacteria.

Treatment involves a single dose of azithromycin (Zithromax) or the use of topical tetracycline (Chromatin) ointment. Infected individuals should be counseled about sanitation and taught simple cleanliness.

Toxoplasmosis (too) is a parasitic infection that causes flu-like symptoms, swollen lymph nodes, and muscle aches and pains that may last from a few days to several weeks. The most common symptoms of ATM lung infection are chronic, dry cough, and shortness of breath.

Other symptoms of ATM lung disease include fatigue, chest pain, malaise, and weakness. As ATM lung disease progresses, fevers, night sweats, and appetite loss may occur.

Treatment guidelines for ATM lung disease depend upon the type and extent of the infection, and the person's health. Antibiotic-resistant infections can lead to longer hospital stays, higher treatment costs, and more deaths.

The main symptoms of COVID-19 -19 infection include cough, fever, and shortness of breath. Occasionally, people infected with COVID-19 -19 may experience diarrhea, a sore throat, a runny or stuffy nose, or aches and pains.

Avoiding contact with infected people, social distancing, not touching your face, frequent handwashing, cleaning, and disinfecting of frequently touched surfaces can help to reduce your risk of contracting the 2019 novel coronavirus. There are two forms of legionellosis: Pontiac fever and Legionnaires' disease, which is the more severe of the two infections.

Symptoms of Legionnaires' disease include cough, chills, fever and sometimes muscle aches, headaches, loss of appetite, diarrhea, and severe pneumonia. While Pontiac fever resolves on its own, Legionnaires' disease must be treated with antibiotics.

Diseases that travelers may pick up from contaminated water or food, insect or animal bites, or from other people include: malaria, meningococcal meningitis, yellow fever, hepatitis A, typhoid fever, polio, and cholera. When you are pregnant, many sexually transmitted diseases (STDs) can be especially harmful to you and your baby.

These STDs include herpes, HIV/AIDS, genital warts (HPV), hepatitis B, chlamydia, syphilis, gonorrhea, and trichomoniasis. Symptoms include bumps, sores, warts, swelling, itching, or redness in the genital region.

Avoiding cigarette smoking, practice good hygiene, stay away from crowds, and alerting your healthcare provider if you have a sinus infection or cold or cough that becomes worse. Treatment options depend upon the severity of the emphysema, bronchitis, or cold combination.

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